Important Safety Information
      
OZURDEX® is a biodegradable implant containing the corticosteroid dexamethasone. Corticosteroids, such as dexamethasone, block chemical pathways that lead to inflammation, leakage from the retinal blood vessels, and edema (swelling) of the retina. OZURDEX® may help reverse some vision loss that may be caused by a retinal vein occlusion (RVO) or by noninfectious uveitis affecting the posterior segment of the eye.
OZURDEX® reduces swelling of the macula

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The first and only injectable, biodegradable dexamethasone implant

A biodegradable implant is one that doesn't need to be removed after it's done working. OZURDEX® biodegradable implants use advanced NOVADUR® drug delivery technology, in which biodegradable material is combined with the active drug dexamethasone to form a tiny rod-shaped implant. Inside the eye, the implant is slowly dissolved in the vitreous gel that fills the eye, releasing dexamethasone.

Special considerations for corticosteroids

Corticosteroids, such as OZURDEX® intravitreal implants, can cause the fluid pressure inside the eye to increase. This is not something you can feel. So, following the injection, your doctor should monitor your eye pressure. If you experience this side effect, treatment such as medicated eyedrops or surgery may be required to lower the pressure.

Some patients who receive OZURDEX® intravitreal implants may develop cataracts or their existing cataracts may worsen. It's important to remember that not treating your condition may lead to irreversible vision loss. You should discuss this issue with your doctor.


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Indications
OZURDEX® (dexamethasone intravitreal implant) is an implant injected into the eye (vitreous) and used:
  • To treat adults with macular edema following branch retinal vein occlusion (BRVO) or central retinal vein occlusion (CRVO)
  • To treat adults with noninfectious uveitis affecting the posterior segment of the eye
Important Safety Information

OZURDEX® should not be used in patients who have any infections or diseases in the eye, or surrounding eye area, including most viral diseases of the cornea and conjunctiva, including active herpes viral infection of the eye, vaccinia, varicella, mycobacterial infections, and fungal diseases.

OZURDEX® should not be used in patients with advanced glaucoma. You should not use OZURDEX® if you are allergic to one of its ingredients.

Injections into the vitreous in the eye are associated with serious eye infection (endophthalmitis), eye inflammation, increased eye pressure, and retinal detachments.

Use of corticosteroids may produce posterior subcapsular cataracts, increased eye pressure, glaucoma, and may increase the establishment of secondary ocular infections due to bacteria, fungi, or viruses.

In the days following injection with OZURDEX®, patients are at risk for potential complications including in particular, but not limited to, the development of serious eye infection or elevated intraocular pressure. If your eye becomes red, sensitive to light, painful, or develops a change in vision, you should seek immediate care from your eye doctor. You may experience temporary visual blurring after receiving an injection and should not drive or use machines until this has resolved.

The most common side effects reported in patients include: increased eye pressure, conjunctival bleeding, eye pain, conjunctival hyperemia, ocular hypertension, cataract, vitreous detachment, and headache.

OZURDEX® is for prescription use only. Individual results with OZURDEX® may vary.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see full prescribing information. Click here.
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